Nandor Ludvig, M,D., Ph.D.

Publications

Publications

1. Kral, John G; Ludvig, Nandor. "Subarachnoid pharmacodialysis for central nervous system disorders". Medical hypotheses. 2013; 80: 105 (#947572)
2. Ludvig N; Medveczky G; Rizzolo R; Tang HM; Baptiste SL; Doyle WK; Devinsky O; Carlson C; French JA; Kral JG; Charchaflieh J; Kuzniecky RI. "An implantable triple-function device for local drug delivery, cerebrospinal fluid removal and EEG recording in the cranial subdural/subarachnoid space of primates". Journal of neuroscience methods. 2012; 203: 275 (#139939)
3. Ludvig, Nandor; Switzer, Robert C 3rd; Tang, Hai M; Kuzniecky, Ruben I. "Autoradiographic evidence for the transmeningeal diffusion of muscimol into the neocortex in rats". Brain research. 2012; 1441: 1 (#158274)
4. Ludvig, Nandor; Tang, Hai M; Baptiste, Shirn L; Medveczky, Geza; Vaynberg, Jonathan K; Vazquez-Derose, Jacqueline; Stefanov, Dimitre G; Devinsky, Orrin; French, Jacqueline A; Carlson, Chad; Kuzniecky, Ruben I. "Long-term behavioral, electrophysiological, and neurochemical monitoring of the safety of an experimental antiepileptic implant, the muscimol-delivering Subdural Pharmacotherapy Device in monkeys". Journal of neurosurgery. 2012; 117: 162 (#171122)
5. Artan, N Sertac; Li, Xiaonin; Patel, Ramesh; Ning, Chengzhi; Ludvig, Nandor; Chao, H Jonathan. "Multi-layer coils for efficient Transcutaneous Power Transfer". Conference Proceedings (IEEE Engineering in Medicine & Biology Society). 2011; 2011: 3031 (#947562)
6. Ludvig, Nandor; Tang, Hai M; Artan, N Sertac; Mirowski, Piotr; Medveczky, Geza; Baptiste, Shirn L; Darisi, Sindhu; Kuzniecky, Ruben I; Devinsky, Orrin; French, Jacqueline A. "Transmeningeal muscimol can prevent focal EEG seizures in the rat neocortex without stopping multineuronal activity in the treated area". Brain research. 2011; 1385: 182 (#129321)
7. Tang, Hai M; French, Jacqueline A; Kuzniecky, Ruben I; Devinsky, Orrin; Ludvig, Nandor. "Periodic transmeningeal muscimol maintains its antiepileptic efficacy over three weeks without inducing tolerance, in rats". Neuroscience letters. 2011; 494: 135 (#130302)
8. Artan, N; Vanjani, Hitesh; Vashist, Gurudath; Fu, Zhen; Bhakthavatsala, Santosh; Ludvig, Nandor; Medveczky, Geza; Chao, H. "A high-performance transcutaneous battery charger for medical implants". Conference Proceedings (IEEE Engineering in Medicine & Biology Society). 2010; 1: 1581 (#115443)
9. Baptiste, Shirn L; Tang, Hai M; Kuzniecky, Ruben I; Devinsky, Orrin; French, Jacqueline A; Ludvig, Nandor. "Comparison of the antiepileptic properties of transmeningeally delivered muscimol, lidocaine, midazolam, pentobarbital and GABA, in rats". Neuroscience letters. 2010; 469: 421 (#106495)
10. Ludvig N.. "Subarachnoid pharmacotherapy for maximizing recovery after cortical ischemic stroke". Journal of experimental stroke & translational medicine. 2010; 3: 13 (#113818)
11. Ludvig, Nandor; Medveczky, Geza; French, Jacqueline A; Carlson, Chad; Devinsky, Orrin; Kuzniecky, Ruben I. "Evolution and prospects for intracranial pharmacotherapy for refractory epilepsies: the subdural hybrid neuroprosthesis". Epilepsy research & treatment. 2010; 2010: 725696 (#177156)
12. Artan, Nabi S.; Mirowski, P.; Tang, H. M.; Medveczky, G.; Baptiste, S. L.; Chao, H. J.; Devinsky, O.; Kuzniecky, R. I.; Ludvig, N.. "DETECTING ABNORMALLY LARGE-AMPLITUDE MULTI-NEURON BURSTS BEFORE FOCAL NEOCORTICAL EEG SEIZURE ONSET IN FREELY BEHAVING RATS". Epilepsia. 2009; 50: 391 (#654632)
13. Ludvig, Nandor; Baptiste, Shirn L; Tang, Hai M; Medveczky, Geza; von Gizycki, Hans; Charchaflieh, Jean; Devinsky, Orrin; Kuzniecky, Ruben I. "Localized transmeningeal muscimol prevents neocortical seizures in rats and nonhuman primates: Therapeutic implications". Epilepsia. 2009; 50: 678 (#95775)
14. Ludvig, Nandor; Tang, H. M.; Baptiste, S. L.; Medveczky, G.; Artan, N. S.; Chao, H. J.; Mirowski, P.; Devinsky, O.; French, J.; Kuzniecky, R. I.. "CELLULAR ELECTROPHYSIOLOGICAL EFFECTS OF SEIZURE-PREVENTING CONCENTRATIONS OF TRANSMENINGEAL MUSCIMOL IN THE RAT NEOCORTEX". Epilepsia. 2009; 50: 390 (#654622)
15. Baptiste, SL; Tang, HM; Devinsky, O; Kuzniecky, RI; Charchaflieh, J; von Gizycki, H; Ludvig, N. "EPIDURAL AND SUBDURAL MUSCIMOL DELIVERIES IN RATS AND MONKEYS, RESPECTIVELY, PREVENT FOCAL SEIZURES AT CONCENTRATIONS THAT CAUSE NO BEHAVIORAL SIDE-EFFECTS". Epilepsia. 2008; 49: 375 (#91398)
16. Fenton, Andre A; Kao, Hsin-Yi; Neymotin, Samuel A; Olypher, Andrey; Vayntrub, Yevgeniy; Lytton, William W; Ludvig, Nandor. "Unmasking the CA1 ensemble place code by exposures to small and large environments: more place cells and multiple, irregularly arranged, and expanded place fields in the larger space". Journal of neuroscience. 2008; 28: 11250 (#95957)
17. Ludvig, Nandor; Sheffield, Lynette G; Tang, Hai M; Baptiste, Shirn L; Devinsky, Orrin; Kuzniecky, Ruben I. "Histological evidence for drug diffusion across the cerebral meninges into the underlying neocortex in rats". Brain research. 2008; 1188: 228 (#79135)
18. Madhavan, Deepak; Mirowski, Piotr; Ludvig, Nandor; Carlson, Chad; Doyle, Werner; Devinsky, Orrin; Kuzniecky, Ruben. "Effects of subdural application of lidocaine in patients with focal epilepsy". Epilepsy research. 2008; 78: 235 (#78353)
19. Tang, HM; Mirowski, P; Baptiste, SL; Devinsky, O; Kuzniecky, RI; Ludvig, N. "EVIDENCE FOR INCREASED NEURONAL ELECTROPHYSIOLOGICAL ACTIVITY BEFORE EEG SEIZURE ONSET IN THE RAT NEOCORTICAL SEIZURE FOCUS". Epilepsia. 2008; 49: 382 (#91399)
20. John, Jenine E; Baptiste, Shirn L; Sheffield, Lynette G; von Gizycki, Hans; Kuzniecky, Ruben I; Devinsky, Orrin; Ludvig, Nandor. "Transmeningeal delivery of GABA to control neocortical seizures in rats". Epilepsy research. 2007; 75: 10 (#72893)
21. Ludvig, N; Tang, HM; Baptiste, SL; Kuzniecky, RI; Devinsky, O. "Neocortical multi-neuron recording as a potential tool for predicting focal seizures". Epilepsia. 2007; 48: 388 (#87156)
22. Madhavan, D; Mirowski, PW; Ludvig, N; Carlson, C; Devinsky, O; Doyle, W; Kuzniecky, R. "Effects of the subdural application of lidocaine on EEG spiking in patients with focal epilepsy". Epilepsia. 2007; 48: 307 (#104242)
23. Sheffield, LG; Baptiste, SL; Tang, HM; Kuzniecky, RI; Devinsky, O; Ludvig, N. "Histological evidence for transmeningeal drug diffusion in the rat cerebral cortex: A study on the neuropathological effects of epidurally delivered NMDA". Epilepsia. 2007; 48: 310 (#87155)
24. Gilbert, Erin; Tang, J Michael; Ludvig, Nandor; Bergold, Peter J. "Elevated lactate suppresses neuronal firing in vivo and inhibits glucose metabolism in hippocampal slice cultures". Brain research. 2006; 1117: 213 (#95958)
25. John, JE; Baptiste, SL; Medveczky, G; von Gizycki, H; Kuzniecky, RI; Devinsky, O; Ludvig, N. "Epidural delivery of the combination of GABA and adenosine terminates locally induced neocortical seizures in rats". Epilepsia. 2006; 47: 219 (#69539)
26. Ludvig, Nandor; Kuzniecky, Ruben I; Baptiste, Shirn L; John, Jenine E; von Gizycki, Hans; Doyle, Werner K; Devinsky, Orrin. "Epidural pentobarbital delivery can prevent locally induced neocortical seizures in rats: the prospect of transmeningeal pharmacotherapy for intractable focal epilepsy". Epilepsia. 2006; 47: 1792 (#69701)
27. von Gizycki, H; Baptiste, SL; Medveczky, G; Kuzniecky, RI; Devinsky, O; Ludvig, N. "Synchrony changes between hippocampal and neocortical EEG signals precede seizure activity induced by intrahippocampal NMDA application in freely behaving rats". Epilepsia. 2006; 47: 47 (#69536)
28. Kovacs, L; Ludvig, N; Devinsky, O; Kuzniecky, RI. "Vector-analysis: Low-power-requiring software for real-time EEG seizure recognition/prediction in hybrid neuroprosthetic devices". Epilepsia. 2005; 46: 317 (#59591)
29. Ludvig, N; Kovacs, L; Medveczky, G; Kuzniecky, RI; Devinsky, O. "Toward the development of a subdural hybrid neuroprosthesis for the treatment of intractable focal epilepsy". Epilepsia. 2005; 46: 270 (#59588)
30. Ludvig, N; Kuzniecky, RI; Moshe, SL; von Gizycki, H; Devinsky, O. "Developing a kainic acid-induced temporal lobe epilepsy model in behaving squirrel monkeys". Epilepsia. 2004; 45: 210 (#49021)
31. Ludvig, Nandor; Tang, Hai M; Gohil, Baiju C; Botero, Juan M. "Detecting location-specific neuronal firing rate increases in the hippocampus of freely-moving monkeys". Brain research. 2004; 1014: 97 (#61904)
32. Ludvig, Nandor; Tang, Hai M; Eichenbaum, Howard; Gohil, Baiju C. "Spatial memory performance of freely-moving squirrel monkeys". Behavioural brain research. 2003; 140: 175 (#61905)
33. Ludvig, Nandor; Kovacs, Lorant; Kando, Laszlo; Medveczky, Geza; Tang, Hai M; Eberle, Lawrence P; Lemon, Charles R. "The use of a remote-controlled minivalve, carried by freely moving animals on their head, to achieve instant pharmacological effects in intracerebral drug-perfusion studies". Brain research protocols. 2002; 9: 23 (#61906)
34. Ludvig, N; Fox, S E; Kubie, J L; Altura, B M; Altura, B T. "Application of the combined single-cell recording/intracerebral microdialysis method to alcohol research in freely behaving animals". Alcoholism: clinical & experimental research. 1998; 22: 41 (#1221352)
35. Ludvig, N; Chao, K; Altura, B T; Altura, B M; Fox, S E. "Manipulation of pyramidal cell firing in the hippocampus of freely behaving rats by local application of K+ via microdialysis". Hippocampus. 1996; 6: 97 (#1221612)
36. Ludvig, N; Altura, B T; Fox, S E; Altura, B M. "The suppressant effect of ethanol, delivered via intrahippocampal microdialysis, on the firing of local pyramidal cells in freely behaving rats". Alcohol. 1995; 12: 417 (#1221682)

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